Tissue distribution and neuroprotective effects of citrus flavonoid tangeretin in a rat model of Parkinson's disease.
Rooprai, Harcharan K., Christidou, M., Datla, K. P. and Widmer, W. W. (2001) Tissue distribution and neuroprotective effects of citrus flavonoid tangeretin in a rat model of Parkinson's disease. Neuroreport, 12 (17) . pp. 3871-3875. ISSN 09594965 [Article] (doi:10.1097/00001756-200112040-00053)
Abstract
This was the first study to give evidence that a citrus flavonoid (tangeretin) crosses the rat blood-brain-barrier and reduces the loss of TH+ cells and dopamine after 6-OHDA lesion in a model for PD. It showed that there was differential regional distribution of tangeretin within the brain and was neuroprotective.
| Item Type: | Article |
|---|---|
| Research Areas: | A. > School of Science and Technology > Natural Sciences |
| ISI Impact: | 46 |
| Item ID: | 519 |
| Depositing User: | Repository team |
| Date Deposited: | 24 Nov 2008 12:39 |
| Last Modified: | 13 Oct 2016 14:11 |
| URI: | https://eprints.mdx.ac.uk/id/eprint/519 |
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