Cytotoxicity of fusobacterium ulcerans

Adriaans, Beverley and Garelick, Hemda ORCID logoORCID: (1989) Cytotoxicity of fusobacterium ulcerans. Journal of Medical Microbiology, 29 (3) . pp. 177-180. ISSN 0022-2615 [Article] (doi:10.1099/00222615-29-3-177)


A new species of Fusobacterium, F. ulcerans, was isolated from 46 tropical ulcers. All the isolates had shown identical soluble cell protein patterns on polyacrylamide gel electrophoresis although there were two morphological types with slightly different biochemical properties. A representative strain of each of the two groups was selected for in- vitro cytotoxicity testing on a range of tissue-culture cell lines. Both strains of F. ulcerans induced a marked cytotoxic effect on Vero and Int-407 cells. This effect may contribute to the pathogenesis of tropical ulcers.

Item Type: Article
Research Areas: A. > School of Science and Technology > Natural Sciences
Item ID: 3777
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Depositing User: Devika Mohan
Date Deposited: 19 Jan 2010 05:29
Last Modified: 06 Jun 2019 09:13

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