Development of a biosensor for fast point-of-care blood analysis of Troponin

Bayford, Richard ORCID logoORCID: https://orcid.org/0000-0001-8863-6385, Damaso, Rui, Jiang, Dai, Rahal, Mohamad and Demosthenous, Andreas ORCID logoORCID: https://orcid.org/0000-0003-0623-963X (2022) Development of a biosensor for fast point-of-care blood analysis of Troponin. 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). In: 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 11-15 Jul 2022, Glasgow, Scotland, United Kingdom. e-ISBN 9781728127828, pbk-ISBN 9781728127835. ISSN 2375-7477 [Conference or Workshop Item] (doi:10.1109/EMBC48229.2022.9871851)

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Abstract

We present the development of novel tetrapolar EIS biosensor for the detect of troponin. Troponin has considerable diagnostic power and provide invaluable prognostic information for risk stratification. of acute coronary syndromes. Clinical Relevance— A feasibility study was undertaken to assess the diagnostic performance of serial cardiac troponin measurements which is excellent as these structural proteins are unique to the heart and thus sensitive and specific of damage to the myocardium. clinical molecular diagnostics and home healthcare. Troponin’s biosensors would provide point-of-care and rapid decision making for the early detection of CS. Clinically relevant window of cTnI testing, concentrations from 10pM to 0.1μM were achieved.

Item Type: Conference or Workshop Item (Paper)
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Research Areas: A. > School of Science and Technology > Natural Sciences > Biophysics and Bioengineering group
Item ID: 36553
Notes on copyright: © 2022 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
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Depositing User: Richard Bayford
Date Deposited: 14 Oct 2022 08:30
Last Modified: 18 Oct 2022 09:13
URI: https://eprints.mdx.ac.uk/id/eprint/36553

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