Monitoring occurrence of SARS-CoV-2 in school populations: A wastewater-based approach
Castro-Gutierrez, Victor, Hassard, Francis, Vu, Milan ORCID: https://orcid.org/0000-0002-6851-7634, Leitao, Rodrigo, Burczynska, Beata
ORCID: https://orcid.org/0000-0003-4101-8525, Wildeboer, Dirk
ORCID: https://orcid.org/0000-0003-1298-7511, Stanton, Isobel, Rahimzadeh, Shadi
ORCID: https://orcid.org/0000-0002-0396-0803, Baio, Gianluca, Garelick, Hemda
ORCID: https://orcid.org/0000-0003-4568-2300, Hofman, Jan, Kasprzyk-Hordern, Barbara, Kwiatkowska, Rachel, Majeed, Azeem, Priest, Sally J.
ORCID: https://orcid.org/0000-0003-2304-1502, Grimsley, Jasmine, Lundy, Lian
ORCID: https://orcid.org/0000-0003-1155-4132, Singer, Andrew C. and Di Cesare, Mariachiara
ORCID: https://orcid.org/0000-0002-3934-3364
(2022)
Monitoring occurrence of SARS-CoV-2 in school populations: A wastewater-based approach.
PLoS One, 17
(6)
, e0270168.
ISSN 1932-6203
[Article]
(doi:10.1371/journal.pone.0270168)
|
PDF
- Published version (with publisher's formatting)
Available under License Creative Commons Attribution 4.0. Download (2MB) | Preview |
Abstract
Clinical testing of children in schools is challenging, with economic implications limiting its frequent use as a monitoring tool of the risks assumed by children and staff during the COVID-19 pandemic. Here, a wastewater-based epidemiology approach has been used to monitor 16 schools (10 primary, 5 secondary and 1 post-16 and further education) in England. A total of 296 samples over 9 weeks have been analysed for N1 and E genes using qPCR methods. Of the samples returned, 47.3% were positive for one or both genes with a detection frequency in line with the respective local community. WBE offers a low cost, non-invasive approach for supplementing clinical testing and can provide longitudinal insights that are impractical with traditional clinical testing.
Item Type: | Article |
---|---|
Sustainable Development Goals: | |
Theme: | |
Keywords (uncontrolled): | Schools, SARS CoV 2, Virus testing, COVID 19, England, Public and occupational health, Children, RNA extraction |
Research Areas: | A. > School of Science and Technology > Natural Sciences |
Item ID: | 35834 |
Useful Links: | |
Depositing User: | Milan Vu |
Date Deposited: | 06 Sep 2022 13:02 |
Last Modified: | 06 Sep 2022 13:06 |
URI: | https://eprints.mdx.ac.uk/id/eprint/35834 |
Actions (login required)
![]() |
View Item |
Statistics
Additional statistics are available via IRStats2.