NOACs added to WHO’s essential medicines list: recommendations for future policy actions

Di Cesare, Mariachiara ORCID: https://orcid.org/0000-0002-3934-3364, Jarvis, Jordan D, Scarlatescu, Oana, Leng, Xinyi, Zaidel, Ezequiel J., Burrone, Esteban, Eiselé, Jean-Luc, Prabhakaran, Dorairaj and Silwa, Karen (2020) NOACs added to WHO’s essential medicines list: recommendations for future policy actions. Global Heart, 15 (1) , 67. pp. 1-6. ISSN 2211-8160 [Article] (doi:10.5334/gh.774)

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Abstract

The introduction of non-vitamin K antagonists oral anticoagulants, a class of medicines which includes dabigatran, apixaban, edoxaban and rivaroxaban, has resulted in improvements in the safety and efficacy of non valvular atrial fibrillation treatment for stroke prevention, with significant reductions in stroke, intracranial haemorrhage, and mortality. For these reasons, a team of World Heart Federation Emerging Leaders led efforts to add non-vitamin K antagonists oral anticoagulants to the World Health Organization’s Model List of Essential Medicines in 2019. Following the inclusion of this class of medicines in the Essential Medicines List, this editorial proposes several recommendations to improve the accessibility, affordability and acceptability of non-vitamin K oral anticoagulants, especially in low- and middle-income settings, in order to successfully manage non-valvular atrial fibrillation and to lower the risk of stroke.

Item Type: Article
Keywords (uncontrolled): WHO essential medicines list, NOACs, access to essential medicines, atrial fibrillation
Research Areas: A. > School of Science and Technology > Natural Sciences
Item ID: 31132
Notes on copyright: © 2020 The Author(s).
This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Depositing User: Mariachiara Di Cesare
Date Deposited: 07 Oct 2020 14:24
Last Modified: 07 Oct 2020 14:24
URI: https://eprints.mdx.ac.uk/id/eprint/31132

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