Towards a system for tracking drug delivery using frequency excited gold nanoparticles

Neshatvar, Nazanin ORCID: https://orcid.org/0000-0002-0658-8883, Damaso, Rui, Seifnaraghi, Nima, Demosthenous, Andreas ORCID: https://orcid.org/0000-0003-0623-963X and Bayford, Richard ORCID: https://orcid.org/0000-0001-8863-6385 (2019) Towards a system for tracking drug delivery using frequency excited gold nanoparticles. Sensors, 19 (21) , 4750. pp. 1-9. ISSN 1424-8220 [Article] (doi:10.3390/s19214750)

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Abstract

Nanoparticle-based drugs are rapidly evolving to treat different conditions and have considerable potential. A new system based on the combination of electrical impedance tomography (EIT) imaging and a power amplifier with a RF coil has been developed to study the effect of gold nanoparticles (AuNPs) when excited in the MHz frequency range. We show that samples including AuNPs have a temperature increase of 1−1.5 °C due to the presence of RF excitation at 13.56 MHz which provides a higher rate of change for solutions without AuNPs. They also show more than a 50% increase in conductivity in difference imaging as the result of this excitation. The change for samples without AuNPs is 40%.

Item Type: Article
Keywords (uncontrolled): drug delivery, electrical impedance tomography (EIT), gold nanoparticles, power amplifier, radio frequency (RF) induction
Research Areas: A. > School of Science and Technology > Natural Sciences > Biophysics and Bioengineering group
Item ID: 28087
Notes on copyright: © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
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Depositing User: Jisc Publications Router
Date Deposited: 04 Nov 2019 09:39
Last Modified: 28 Aug 2020 11:28
URI: https://eprints.mdx.ac.uk/id/eprint/28087

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