Towards a system for tracking drug delivery using frequency excited gold nanoparticles
Neshatvar, Nazanin ORCID: https://orcid.org/0000-0002-0658-8883, Damaso, Rui, Seifnaraghi, Nima, Demosthenous, Andreas
ORCID: https://orcid.org/0000-0003-0623-963X and Bayford, Richard
ORCID: https://orcid.org/0000-0001-8863-6385
(2019)
Towards a system for tracking drug delivery using frequency excited gold nanoparticles.
Sensors, 19
(21)
, 4750.
pp. 1-9.
ISSN 1424-8220
[Article]
(doi:10.3390/s19214750)
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Abstract
Nanoparticle-based drugs are rapidly evolving to treat different conditions and have considerable potential. A new system based on the combination of electrical impedance tomography (EIT) imaging and a power amplifier with a RF coil has been developed to study the effect of gold nanoparticles (AuNPs) when excited in the MHz frequency range. We show that samples including AuNPs have a temperature increase of 1−1.5 °C due to the presence of RF excitation at 13.56 MHz which provides a higher rate of change for solutions without AuNPs. They also show more than a 50% increase in conductivity in difference imaging as the result of this excitation. The change for samples without AuNPs is 40%.
Item Type: | Article |
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Keywords (uncontrolled): | drug delivery, electrical impedance tomography (EIT), gold nanoparticles, power amplifier, radio frequency (RF) induction |
Research Areas: | A. > School of Science and Technology > Natural Sciences > Biophysics and Bioengineering group |
Item ID: | 28087 |
Notes on copyright: | © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
Useful Links: | |
Depositing User: | Jisc Publications Router |
Date Deposited: | 04 Nov 2019 09:39 |
Last Modified: | 13 Sep 2022 08:51 |
URI: | https://eprints.mdx.ac.uk/id/eprint/28087 |
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