Evaluation of the effectiveness of Eladi Keram for the treatment of acne vulgaris: a randomised controlled pilot study
Appiah, Sandra S. 
ORCID: https://orcid.org/0000-0002-7497-3388, Lawley, Benjamin, Vu, Milan ORCID: https://orcid.org/0000-0002-6851-7634, Bell, Celia M. ORCID: https://orcid.org/0000-0002-3270-7081 and Jones, Huw ORCID: https://orcid.org/0000-0003-0024-864X
(2017)
Evaluation of the effectiveness of Eladi Keram for the treatment of acne vulgaris: a randomised controlled pilot study.
European Journal of Integrative Medicine, 12
.
pp. 38-43.
ISSN 1876-3820
[Article]
(doi:10.1016/j.eujim.2017.04.004)
|
PDF
- Final accepted version (with author's formatting)
Available under License Creative Commons Attribution-NonCommercial-NoDerivatives 4.0. Download (790kB) | Preview |
Abstract
Introduction: Acne is a multifactorial and common skin disease which can significantly affect the quality of life of sufferers. In this study, a topical herbal preparation traditionally used in Ayurvedic medicine was evaluated as a treatment for individuals with acne on their shoulders and backs.
Methods: Study participants were randomly assigned either to treatment (Eladi Keram) or vehicle control (coconut oil) groups under double blind conditions and instructed on its daily home application. Standardised lesion counting and acne grading were conducted in accordance with US Food and Drug Administration guidelines and with reference to the Leeds Acne Grading Technique. Participants were assessed for severity of the condition at commencement and on day 28 of treatment.
Results: The treatment group showed improvements of 42% (p < 0.005) on the Investigators Global Assessment scale, a 60% (p < 0.05) reduction in inflammatory lesions, a 59% (p < 0.05) reduction in non-inflammatory lesions, and a 59% (p < 0.005) reduction in combined lesion count. The control group showed no statistically significant changes for these criteria.
Conclusion: This study is the first reported clinical evaluation of Eladi Keram as a treatment for acne and findings suggest that it could be effective in reducing inflammatory and non-inflammatory lesions, warranting further investigation by means of a larger scale clinical trial.
| Item Type: | Article |
|---|---|
| Research Areas: | A. > School of Science and Technology > Natural Sciences |
| Item ID: | 22971 |
| Notes on copyright: | © 2017. This author's accepted manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Useful Links: | |
| Depositing User: | Sandra Appiah |
| Date Deposited: | 20 Nov 2017 12:59 |
| Last Modified: | 29 Nov 2022 20:52 |
| URI: | https://eprints.mdx.ac.uk/id/eprint/22971 |
Actions (login required)
 |
View Item |
Statistics
Additional statistics are available via IRStats2.
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)