Quantitative verification of implantable cardiac pacemakers over hybrid heart models

Chen, Taolue, Diciolla, Marco, Kwiatkowska, Marta Z. and Mereacre, Alexandru (2014) Quantitative verification of implantable cardiac pacemakers over hybrid heart models. Information and Computation, 236 . pp. 87-101. ISSN 0890-5401 [Article] (doi:10.1016/j.ic.2014.01.014)

Abstract

We develop a model-based framework which supports approximate quantitative verification of implantable cardiac pacemaker models over hybrid heart models. The framework is based on hybrid input–output automata and can be instantiated with user-specified pacemaker and heart models. For the specifications, we identify two property patterns which are tailored to the verification of pacemakers: “can the pacemaker maintain a normal heart behaviour?” and “what is the energy level of the battery after t time units?”. We implement the framework in Simulink based on the discrete-time simulation semantics and endow it with a range of basic and advanced quantitative property checks. The advanced property checks include the correction of pacemaker mediated Tachycardia and how the noise on sensor leads influences the pacing level. We demonstrate the usefulness of the framework for safety assurance of pacemaker software by instantiating it with two hybrid heart models and verifying a number of correctness properties with encouraging experimental results.

Item Type: Article
Additional Information: Special Issue on Hybrid Systems and Biology
Research Areas: A. > School of Science and Technology > Computer Science > Foundations of Computing group
Item ID: 14737
Depositing User: Taolue Chen
Date Deposited: 22 Apr 2015 16:34
Last Modified: 30 May 2019 18:34
URI: https://eprints.mdx.ac.uk/id/eprint/14737

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