Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3

Nicolaou, K. C., Frederick, Michael O., Petrovic, Goran, Cole, K. P. and Loizidou, Erika ORCID: https://orcid.org/0000-0002-4834-6639 (2006) Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3. Angewandte Chemie International Edition, 45 (16) . pp. 2609-2615. ISSN 1433-7851 [Article] (doi:10.1002/anie.200600295)

Abstract

The 39 steps: The recently proposed revised structures of azaspiracid-2 and -3 (see picture), the two most potent members of the azaspiracid family, have been confirmed through the total syntheses of the two compounds. These 39-step syntheses represent a major improvement over the first-generation synthesis of azaspiracid-1 (50 steps).

Item Type: Article
Research Areas: A. > School of Science and Technology > Natural Sciences
Item ID: 14367
Depositing User: Erika Loizidou
Date Deposited: 06 Mar 2015 11:21
Last Modified: 13 Oct 2016 14:32
URI: https://eprints.mdx.ac.uk/id/eprint/14367

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