Beta human chorionic gonadotrophin in serum and urine. A marker for metastatic urothelial cancer.

Iles, Ray K. and Jenkins, B. J. and Oliver, R. T. and Blandy, J. P. and Chard, Tim (1989) Beta human chorionic gonadotrophin in serum and urine. A marker for metastatic urothelial cancer. British Journal of Urology, 64 (3). pp. 241-244. ISSN 1464-4096

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Abstract

Beta human chorionic gonadotrophin (beta HCG) was measured in 127 urine and 85 serum samples from 175 untreated patients with urothelial cancer. Serum levels of beta HCG were substantially elevated in 16 of 21 patients (76%) with widespread metastases but in only 2 of 64 patients (3%) with disease confined to the pelvis. Urine beta HCG levels were moderately raised in 11 of 25 patients (44%) with locally advanced disease, but greatly elevated in 5 of 7 patients (71%) with metastases. Measurement of serum and/or urine beta HCG appears to be an efficient diagnostic marker for the presence of distant metastases in bladder carcinoma.

Item Type:Article
Research Areas:School of Science and Technology > Natural Sciences
ID Code:6115
Deposited On:23 Jun 2010 14:13
Last Modified:11 Oct 2013 05:11

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