In vitro secretion of human chorionic gonadotrophin by bladder tumour cells.
Iles, Ray K. and Oliver, R.T.D. and Kitau, M. and Walker, C. and Chard, Tim (1987) In vitro secretion of human chorionic gonadotrophin by bladder tumour cells. British journal of cancer, 55 (6). pp. 623-626. ISSN 0007-0920
Official URL: http://tinyurl.com/32cqej8
This item is available in the Library Catalogue
Human chorionic gonadotrophin (hCG) and alphafetoprotein (AFP) were measured in culture media from a panel of 29 cell lines including 9 bladder carcinomas, 5 'normal' bladder epithelia, 10 germ cell tumours, and 5 miscellaneous tumours and 'normal' cell lines. In 7 of the 9 bladder carcinomas and 4 of the 5 'normal' bladder epithelia, the media contained hCG at levels ranging from between 34 and 3,600 IU l(-1). All other cell lines, including the 10 germ cell tumour lines gave negative results for hCG. These findings indicate that in vitro secretion of hCG is a common feature of normal and neoplastic bladder transitional epithelia, and support the hypothesis that parts of the genito-urinary epithelium have a potential for hCG production.
|Research Areas:||Science & Technology > Biomedical Science|
|Permissions granted by publisher:||PMC free access|
|Deposited On:||23 Jun 2010 13:09|
|Last Modified:||11 Oct 2013 05:14|
Repository Staff Only: item control page
Full text downloads (NB count will be zero if no full text documents are attached to the record)
Downloads per month over the past year