Limited evolutionary conservation of imprinting in the human placenta

Hills, Frank and Apostolidou, S. and Arnaud, Philippe and Monk, David (2006) Limited evolutionary conservation of imprinting in the human placenta. Proceedings of the National Academy of Sciences, 103 (17). pp. 6623-6628. ISSN 1091-6490

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Abstract

This study demonstrated that orthologues of imprinted mouse genes are not imprinted in the human placenta. This difference correlates with alterations in histone modification. This study is important for understanding of the evolution of mammalian genomic imprinting.

Item Type:Article
Research Areas:Middlesex University Schools and Centres > School of Science and Technology > Natural Sciences
Middlesex University Schools and Centres > School of Health and Education > Centre for Investigative and Diagnostic Oncology
Middlesex University Schools and Centres > School of Science and Technology > Natural Sciences > Reproductive Biology group
Middlesex University Schools and Centres > School of Science and Technology > Natural Sciences > Biomarkers for Cancer group
Citations on ISI Web of Science:109
ID Code:507
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Deposited On:21 Nov 2008 15:45
Last Modified:27 Oct 2014 17:29

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