Limited evolutionary conservation of imprinting in the human placenta

Hills, Frank and Apostolidou, S. and Arnaud, Philippe and Monk, David (2006) Limited evolutionary conservation of imprinting in the human placenta. Proceedings of the National Academy of Sciences, 103 (17). pp. 6623-6628. ISSN 1091-6490

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Abstract

This study demonstrated that orthologues of imprinted mouse genes are not imprinted in the human placenta. This difference correlates with alterations in histone modification. This study is important for understanding of the evolution of mammalian genomic imprinting.

Item Type: Article
Research Areas: A. > School of Health and Education > Centre for Investigative and Diagnostic Oncology
A. > School of Science and Technology > Natural Sciences
A. > School of Science and Technology > Natural Sciences > Biomarkers for Cancer group
A. > School of Science and Technology > Natural Sciences > Reproductive Biology group
ISI Impact: 109
Item ID: 507
Useful Links:
Depositing User: Repository team
Date Deposited: 21 Nov 2008 15:45
Last Modified: 13 Oct 2016 14:11
URI: http://eprints.mdx.ac.uk/id/eprint/507

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