Smooth muscle cholinergic denervation hypersensitivity in diverticular disease.

Ghali, Lucy and Belai, A. and Burleigh, D. E. and Golder, M. (2003) Smooth muscle cholinergic denervation hypersensitivity in diverticular disease. The Lancet, 361 (9373). pp. 1945-1951. ISSN 1474-547X

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Abstract

This paper estabished that choline acetyltransferase was lower in circular muscle from patients with diverticular disease. However M3 receptor levels were upregulated. This may explain increased sponteaous contraction in muscle associated with this diseae and hence its moleculae aetiology.

Item Type:Article
Research Areas:School of Science and Technology > Natural Sciences
School of Science and Technology > Natural Sciences > Biomarkers for Cancer group
Citations on ISI Web of Science:39
ID Code:505
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Deposited On:21 Nov 2008 15:34
Last Modified:24 Oct 2014 15:39

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