Smooth muscle cholinergic denervation hypersensitivity in diverticular disease.
Ghali, Lucy and Belai, A. and Burleigh, D. E. and Golder, M. (2003) Smooth muscle cholinergic denervation hypersensitivity in diverticular disease. The Lancet, 361 (9373). pp. 1945-1951. ISSN 1474-547X
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This paper estabished that choline acetyltransferase was lower in circular muscle from patients with diverticular disease. However M3 receptor levels were upregulated. This may explain increased sponteaous contraction in muscle associated with this diseae and hence its moleculae aetiology.
|Research Areas:||School of Science and Technology > Natural Sciences|
|Citations on ISI Web of Science:||39|
|Deposited On:||21 Nov 2008 15:34|
|Last Modified:||06 Feb 2013 11:45|
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