Comparison of edmonston-zagreb and schwarz strains of measles vaccine given by aerosol or subcutaneous injection
Khanum, Sultana and Garelick, Hemda and Nasir, Uddin and Mann, George and Tomkins, Andrew (1987) Comparison of edmonston-zagreb and schwarz strains of measles vaccine given by aerosol or subcutaneous injection. The Lancet, 329 (8525). pp. 150-153. ISSN 0140-6736
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Official URL: http://dx.doi.org/10.1016/S0140-6736(87)91978-7
The serological response to measles vaccine was tested in Bangladesh in groups of infants aged 4-6 months who received equal doses of Edmonston-Zagreb or Schwarz vaccine by subcutaneous injection or by aerosol. Seroconversion (as measured by the haemagglutination test) occurred in 62% of infants receiving Edmonston-Zagreb strain by injection compared with only 37% of those receiving Schwarz strain. Seroconversion occurred in 35% of those given Edmonston-Zagreb and 34% of those given Schwarz vaccine by aerosol. Edmonston-Zagreb strain appears more effective than Schwarz vaccine in this population and further studies are indicated in other populations where early measles immunisation is desirable.
|Research Areas:||School of Science and Technology > Natural Sciences|
|Citations on ISI Web of Science:||47|
|Deposited On:||21 Jan 2010 06:00|
|Last Modified:||13 May 2014 15:52|
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