Comparison of edmonston-zagreb and schwarz strains of measles vaccine given by aerosol or subcutaneous injection

Khanum, Sultana, Garelick, Hemda, Nasir, Uddin, Mann, George and Tomkins, Andrew (1987) Comparison of edmonston-zagreb and schwarz strains of measles vaccine given by aerosol or subcutaneous injection. The Lancet, 329 (8525). pp. 150-153. ISSN 0140-6736

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Abstract

The serological response to measles vaccine was tested in Bangladesh in groups of infants aged 4-6 months who received equal doses of Edmonston-Zagreb or Schwarz vaccine by subcutaneous injection or by aerosol. Seroconversion (as measured by the haemagglutination test) occurred in 62% of infants receiving Edmonston-Zagreb strain by injection compared with only 37% of those receiving Schwarz strain. Seroconversion occurred in 35% of those given Edmonston-Zagreb and 34% of those given Schwarz vaccine by aerosol. Edmonston-Zagreb strain appears more effective than Schwarz vaccine in this population and further studies are indicated in other populations where early measles immunisation is desirable.

Item Type: Article
Research Areas: A. > School of Science and Technology > Natural Sciences
ISI Impact: 47
Item ID: 3812
Useful Links:
Depositing User: Devika Mohan
Date Deposited: 21 Jan 2010 06:00
Last Modified: 13 Oct 2016 14:16
URI: https://eprints.mdx.ac.uk/id/eprint/3812

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