Hepatitis C viraemia in adults with type 2 autoimmune hepatitis.
Garson, Jeremy A. and Lenzi, M. and Ring, Christopher J. and Cassani, F. and Ballardini, G. and Briggs, M. and Tedder, Richard S. and Bianchi, F. B. (1991) Hepatitis C viraemia in adults with type 2 autoimmune hepatitis. Journal of medical virology, 34 (4). pp. 223-6. ISSN 0146-6615
Full text is not in this repository.
Sera from 14 patients with type 2 autoimmune hepatitis (anti-LKM1 positive) were investigated for evidence of hepatitis C virus (HCV) infection. Antibodies to HCV were detected in 13 patients by both commercial and "in-house" ELISAs and also by a second generation recombinant immunoblot assay. Nine of the 13 (69%) anti-HCV positive patients were shown to be viraemic by a polymerase chain reaction-based assay for serum HCV RNA. Neither anti-HCV nor serum HCV RNA were detected in any of 6 controls with primary biliary cirrhosis or in 39 healthy blood donors. These findings strongly suggest a role for HCV in the pathogenesis of type 2 autoimmune hepatitis.
|Research Areas:||A. > School of Science and Technology > Natural Sciences|
|Deposited On:||03 Dec 2009 14:34|
|Last Modified:||24 Mar 2015 13:11|
Repository staff only: item control page
Full text downloads (NB count will be zero if no full text documents are attached to the record)
Downloads per month over the past year