Improving health literacy about Tuberculosis among drug users. A pilot randomized controlled trial

Aceijas, Carmen, Weaver, Tim ORCID: https://orcid.org/0000-0002-3437-3556, Baez-Caraballo, Pamela, Cummings, Nerissa and Devi Sowamber, Neelam (2019) Improving health literacy about Tuberculosis among drug users. A pilot randomized controlled trial. Drug Dependence and Addiction (1). pp. 8-18.

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Abstract

Introduction: Despite effective treatment, tuberculosis remains among the top-10 causes of death causing ~1.3 million deaths in 2017. Furthermore, tuberculosis infection rates have increased amongst excluded populations such as people misusing substances.

Objectives and design: We conducted a two London sites pilot randomized controlled trial to test interventions, recruitment, attrition rates and assessment procedures of a parallel, three-arms controlled trial to assess the effectiveness of tuberculosis health literacy interventions among drug dependent (heroin, crack cocaine or heroin and crack cocaine) population in treatment.

Results: Forty-two subjects were recruited to the pilot trial (response rate = 26%) and randomized to three interventions (1st: Information booklet; 2nd: Interactive seminar; 3rd: Interactive seminar + contingency management targeting tuberculosis-health-related action). Baseline and post-intervention tuberculosis knowledge scores were obtained and re-assessed at 2-months follow up. The overall attrition rate was 43%. The knowledge scale had good internal reliability (Cronbach’s α = 0.7). Statistically significant increases in knowledge scores (baseline to post-intervention = 5.9 points, baseline to follow-up = 4.3) were recorded for the whole sample (CI = 99%; p < 0.001 for both analysis), but no statistically significant differences between-groups were observed (p = 0.7). Half of participants in the contingency management group achieved their health-action targets.

Conclusion: Health literacy interventions to increase knowledge about tuberculosis among drug users are feasible and achieve promising increases in knowledge and health-related actions but measures to prevent a high attrition rate in a large-scale trial must be introduced. The absence of difference between trial-group outcomes suggests low-intensity interventions may achieve knowledge gain too. Further investigation of contingency management to promote tuberculosis-related health behaviours is needed.

Item Type: Article
Research Areas: A. > School of Science and Technology > Natural Sciences
Item ID: 26741
Notes on copyright: Copyright © 2019 Carmen Aceijas et al. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and work is properly cited.
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Depositing User: Carmen Aceijas
Date Deposited: 07 Jun 2019 13:43
Last Modified: 11 Jun 2019 21:08
URI: https://eprints.mdx.ac.uk/id/eprint/26741

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