Evaluation of the effectiveness of Eladi Keram for the treatment of acne vulgaris: a randomised controlled pilot study

Appiah, Sandra S. and Lawley, Benjamin and Vu, Milan and Bell, Celia M. and Jones, Huw (2017) Evaluation of the effectiveness of Eladi Keram for the treatment of acne vulgaris: a randomised controlled pilot study. European Journal of Integrative Medicine, 12 . pp. 38-43. ISSN 1876-3820

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Introduction: Acne is a multifactorial and common skin disease which can significantly affect the quality of life of sufferers. In this study, a topical herbal preparation traditionally used in Ayurvedic medicine was evaluated as a treatment for individuals with acne on their shoulders and backs.

Methods: Study participants were randomly assigned either to treatment (Eladi Keram) or vehicle control (coconut oil) groups under double blind conditions and instructed on its daily home application. Standardised lesion counting and acne grading were conducted in accordance with US Food and Drug Administration
guidelines and with reference to the Leeds Acne Grading Technique. Participants were assessed for severity of the condition at commencement and on day 28 of treatment.

Results: The treatment group showed improvements of 42% (p < 0.005) on the Investigators Global Assessment scale, a 60% (p < 0.05) reduction in inflammatory lesions, a 59% (p < 0.05) reduction in non-inflammatory lesions, and a 59% (p < 0.005) reduction in combined lesion count. The control group showed no statistically
significant changes for these criteria.

Conclusion: This study is the first reported clinical evaluation of Eladi Keram as a treatment for acne and findings suggest that it could be effective in reducing inflammatory and non-inflammatory lesions, warranting further investigation by means of a larger scale clinical trial.

Item Type: Article
Research Areas: A. > School of Science and Technology > Natural Sciences
Item ID: 22971
Useful Links:
Depositing User: Sandra Appiah
Date Deposited: 20 Nov 2017 12:59
Last Modified: 15 Nov 2018 04:12
URI: http://eprints.mdx.ac.uk/id/eprint/22971

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