FOXM1 is a downstream target of Gli1 in basal cell carcinomas

Teh, Muy-Teck and Wong, Soon-Tee and Neill, Graham W. and Ghali, Lucy and Philpott, Michael P. and Quinn, Anthony G. (2002) FOXM1 is a downstream target of Gli1 in basal cell carcinomas. Cancer Research, 62 (16). pp. 4773-4780. ISSN 0008-5472

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Abstract

Gli1 has now been implicated in switching between motility and static cell replication. FOXM1 is involved in cell replication of cutaneous tissue and BCC. This study established that GLi1 upregulates FOXM1 and by inference cutaneous cell replication.

Item Type:Article
Research Areas:School of Science and Technology > Natural Sciences
School of Science and Technology > Natural Sciences > Biomarkers for Cancer group
Citations on ISI Web of Science:162
ID Code:229
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Deposited On:30 Oct 2008 11:32
Last Modified:24 Oct 2014 15:39

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