FOXM1 is a downstream target of Gli1 in basal cell carcinomas.
Teh, Muy-Teck, Wong, Soon-Tee, Neill, Graham W., Ghali, Lucy, Philpott, Michael P. and Quinn, Anthony G. (2002) FOXM1 is a downstream target of Gli1 in basal cell carcinomas. Cancer Research, 62 (16). pp. 4773-4780. ISSN 0008-5472
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Gli1 has now been implicated in switching between motility and static cell replication. FOXM1 is involved in cell replication of cutaneous tissue and BCC. This study established that GLi1 upregulates FOXM1 and by inference cutaneous cell replication.
|Research Areas:||Science & Technology > Biomedical Science|
|Citations on ISI Web of Science:||162|
|Deposited On:||30 Oct 2008 11:32|
|Last Modified:||06 Feb 2013 11:45|
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