A conceptual object modelling of gene mutation data.

Rahman, Shahedur and Khan, Nawaz (2001) A conceptual object modelling of gene mutation data. In: Computer science and biology: proceedings of the German conference on bioinformatics. Wingender, Edgar , ed. German Research Center for Biotechnology., Braunschweig, pp. 187-190. ISBN 3000081143

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Official URL: http://www.bioinfo.de/isb/gcb01/poster/index.html

Abstract

For a biomedical and drug development related research, it is essential to analyse the complete data set of human gene mutation data to understand the underlying molecular mechanism of diseases. The gene mutation database [Cooper et al. 1998] represents a rich source of information and it contains a huge number of entries. However, it lacks the complete data sets which is essential to analyse the trait for indirect association of diseases. A typical example in this context would be to analyse the Recombination Fraction () and Relative Dinucleotide Mutabilities (rdm) [Cooper and Krawczak, 1993]. Paton et al. (2000) developed a conceptual model for genomic and related functional data sets, but they used genome data warehouses to implement the model. However, it is evident that data warehouses produce data redundancy and attribute overlapping. Here the paper proposes the theoretical concept for an object model of gene mutation data. The initial outline of this conceptual model interpreting an integrated co-operative framework had been proposed in another paper [Khan et al., 2001].

Item Type:Book Section
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Conference held on October 7 - 10, 2001, Braunschweig.

Research Areas:Middlesex University Schools and Centres > School of Science and Technology > Computer and Communications Engineering
ID Code:1849
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Deposited On:08 Apr 2009 13:01
Last Modified:21 Nov 2014 17:16

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