Evaluation of β-alanine- and GABA-substituted peptides as inhibitors of disease-linked protein aggregation

Madine, Jillian, Wang, Xiaoyan, Brown, David R. and Middleton, David A. (2009) Evaluation of β-alanine- and GABA-substituted peptides as inhibitors of disease-linked protein aggregation. ChemBioChem, 10 (12). pp. 1982-1987. ISSN 1439-4227

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Abstract

Inhibition of amyoid formation - the β-peptide way: Introducing β-amino acids into short peptides is presented as a novel method of preventing aggregation of amyloid proteins. The data suggest a common precursor to design agents to treat Lewy body disease, Alzheimer's and type 2 diabetes.

Item Type: Article
Research Areas: A. > School of Science and Technology > Natural Sciences
Item ID: 12497
Depositing User: Users 3197 not found.
Date Deposited: 07 Nov 2013 12:09
Last Modified: 13 Oct 2016 14:29
URI: https://eprints.mdx.ac.uk/id/eprint/12497

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