Polyoma virus middle T antigen and its role in identifying cancer-related molecules

Dilworth, Stephen M. (2002) Polyoma virus middle T antigen and its role in identifying cancer-related molecules. Nature Reviews Cancer, 2 (12). pp. 951-956. ISSN 1474-175X

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Abstract

Most cancer researchers take for granted some of the basic concepts about the molecular changes that underlie tumorigenesis. These include the principles that tyrosine kinases and the phosphorylation of phosphatidylinositol by phosphatidylinositol 3-kinases are important in the signalling pathways that control proliferation and apoptosis, and hence cancer formation. However, how many know that a small DNA mouse virus was crucial in establishing both of these tenets?

Item Type: Article
Research Areas: A. > School of Science and Technology > Natural Sciences > Molecular Biology group
A. > School of Science and Technology > Natural Sciences
Item ID: 10104
Useful Links:
Depositing User: Professor Stephen M. Dilworth
Date Deposited: 19 Feb 2013 08:54
Last Modified: 13 Oct 2016 14:26
URI: https://eprints.mdx.ac.uk/id/eprint/10104

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